Excessive gingival bleeding in two patients with glanzmann thrombasthenia

Creative Commons License

Toygar H. U., Guzeldemir E.

JOURNAL OF PERIODONTOLOGY, cilt.78, sa.6, ss.1154-1158, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 6
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1902/jop.2007.060393
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1154-1158
  • Anahtar Kelimeler: gingival bleeding, glanzmann thrombasthenia, oral hygiene
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Background: Glanzmann thrombasthenia (GT) is an exceedingly rare but well-defined inherited disorder of platelet function caused by a defect in the glycoprotein IIb/IIIa complex. The association of GT with consanguinity has been noted, especially in geographic regions in which intermarriage is common. In most patients, GT is diagnosed during early infancy or before the age of 5 years. Common manifestations of this disorder are gingival hemorrhage, purpura, epistaxis, petechiae, and menorrhagia. Chronic, prolonged, untreated, or unsuccessfully treated bleeding may be life threatening.