Akademik Veri Yönetim Sistemi
Yardımoğlu Yılmaz M. (Yürütücü), İlbay G.
Yükseköğretim Kurumları Destekli Proje, 1999 - 2000
The aim of this study was to investigate neuron-specific enolase (NSE) immunoreactivity of the different brain regions after pentylenetetrazol (PTZ)- induced epileptic
seizures in rats. Light microscopic examinations provided evidences for changes
of neuronal activity after single and repeated seizures. The number of NSE
(+) cells was well correlated with Nissl staining. The results suggest that NSE
immunoreactivity may be a valuable marker for determination of the number of
metabolically active neurons in different brain regions after single and repeated
experimental seizures.
Keywords epileptic seizure, neuron specific enolase, nissl, pentylenetetrazol, rat
brain