Use of alendronate in the treatment of vitamin D intoxication in infants


Hatun S., Cizmecioglu F. M.

TURKISH JOURNAL OF PEDIATRICS, vol.47, no.4, pp.373-375, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 4
  • Publication Date: 2005
  • Title of Journal : TURKISH JOURNAL OF PEDIATRICS
  • Page Numbers: pp.373-375

Abstract

Vitamin D intoxication remains a challenging problem due to lack of an efficient treatment. Bisphosphonates, inhibitors of osteoclast-mediated bone resorption, however, have been proposed as a safe and effective alternative in the treatment of vitamin D intoxication. We present here two infants with vitamin D intoxication who were successfully treated with alendronate. We propose that oral alendronate is an alternative to intravenous bisphosphonates in the treatment of vitamin D intoxication in infancy.