A convenient synthesis of 3,4-disubstituted-1,2,4-thiadiazole-5(4H)-thiones


Agirbas H., Kahraman K.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.134, ss.381-389, 1998 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 134
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1080/10426509808545478
  • Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Sayfa Sayıları: ss.381-389

Özet

3,4-Disubstituted-1,2,4-oxadiazole-5(4H)-ones were obtained from the reaction of substituted amide oximes with ethylchloroformate. These compounds were treated with P2S5 to give corresponding 1,2,4-oxadiazole-5-thiones. Rearrangement of 1,2,4-oxadiazole-5-thiones, catalysed by metallic copper, yielded 1,2,4-thiadiazole-5-ones. The reaction of 1,2,4-thiadiazole-5-ones with P2S5 gave 1,2,4-thiadiazole-5-thiones.