Synthesis of 3,5-disubstituted-5,6-dihydro-4H-1,2,5-oxadiazine-6-thiones and 3,5-disubstituted-1,2,4-thiadiazoles


Agirbas H., Durust Y., Karahasanoglu A.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.114, ss.173-178, 1996 (SCI-Expanded) identifier identifier

Özet

3,5-Disubstituted-5,6-dihydro-4H-1,2,5-oxadiazine-6-thiones are prepared by the reaction of acetophenone oximes with thiophosgene. The thermal rearrangement of 3-phenyl-5-(p-tolyl)-5,6-dihydro-4H-1,2,5- oxadiazine-6-thione yields the corresponding 1,2,5-thiadiazine-6-one. The reaction of 3-substituted-1,2,4-thiadiazoles with various reactants gave 3,4-disubstituted-1,2,4-thiadiazoles.