Investigation of inhibitory effects of triazole derivatives on the protease enzymes

Akin M., Nalbantoglu S., Arabaci G., Saki N.

RESEARCH JOURNAL OF BIOTECHNOLOGY, cilt.9, ss.19-23, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 9 Konu: 3
  • Basım Tarihi: 2014
  • Sayfa Sayıları: ss.19-23


Triazoles constitute an important class of heterocyclic organic compounds because of their wide range of applications as pharmaceutical agents. They have common mode of action like inhibiting ergosterol synthesis, decreasing adhesion potential of pathogen cells to host tissues and morphogenetic transformation of yeasts to mycelial form. Fungicidal properties of azole agents have been known for many years, however, the investigation of inhibitiory effects of these molecules on various enzymes has increased in recent years. As being the most important group of industrial enzymes, proteases have received significant interest in the food, pharmaceutical and detergent industries.