An Imperious Result of Ischemia Reperfusion Injury: Case Report

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Yaşar E. K. , Alagöz M. Ş.

The 4th congress of Asian Pacific Federation of societies for reconstructive microsurgery, Antalya, Turkey, 9 - 13 May 2018, pp.330-332

  • Publication Type: Conference Paper / Full Text
  • City: Antalya
  • Country: Turkey
  • Page Numbers: pp.330-332
  • Kocaeli University Affiliated: Yes



Emrah Kagan Yasar, Aykut Gök, Mehdi Asadov, Murat Şahin Alagoz

Department of Plastic, Reconstructive and Aesthetic Surgery, Kocaeli University Medical Faculty, Kocaeli, Turkey

ıntroduction Ischemia reperfusion (IR) injury is a devastating situation which especially causes by prolonged warm ischemia.

The process between injury and replantation timing is very important for success. IR is inevitable out of delayed transfer to

medical center or prolonged replantation timing.

CASE: 45 years old woman was consulted with transmetacarpal left hand total amputation caused by a sharp blade injury

while working for 7 hours before. Physical examination shows no other signs or symptoms about other systems, and no any

drug usage was informed.

Patient and amputated part of the hand have been sent to operation room immediately after the end of preoperative workup.

FINDINGS: Amputation was at medial metacarpal level and dorsal oblique, Amputatta had no extra fractures. Proximal

and distal common digital arteries and nerves were placed in the operation and dorsal venules were marked. A total

of 3 arteries, 4 veins anastomosis, and 5 nerves coaptation were performed after bone fixation with kischner wires.

Repair of the flexor and extensor tendons was left for the next session. Despite the venous appearance in the early

postoperative period in the amputate dorsum, the rest of the amputate generally had normal capillarity and bright

appearance. After the control of the circulation, the operation was terminated and the patient was clinically followed

up by medical treatment. Until the 4th day postoperatively, there were no problems except the minimal bleeding from

the wound lips and the ischemic part of the dorsum. On the 5th day amputat was seen refilling the capillary fast. On the

6th day the amount of bleeding from the wound lips increased and exfoliation and bullae began to appear on the skin.

Necrosis began to sit on the amputate dorsum. Reexploration was not considered for the patient who was evaluated as

ischemia reperfusion injury. On day 8, there was a necrotic appearance in volcano and the replated tissue was evaluated

as total necrosis on the 9th day. The necrotic tissue was amputated and the tissue defect was repaired by inguinal flap.

RESULT: Ischemia reperfusion injury is a pathological condition that is mentioned very often but not frequently. Rapid

transfer and fast surgical ischemia are the measures to minimize the damage of reperfusio.. Especially the length of the

warm ischemia and the approach of the amputation level to the proximal can make the risk of ischemia reperfusion injury


 Keywords: Ischemia reperfusion injury, warm ischemia, replantation