Cathelicidin (LL-37) and human 2-defensin levels of children with post-infectious bronchiolitis obliterans


Gedik A. H. , ÇAKIR E., GÖKDEMİR Y., Uyan Z. S. , KOÇYİĞİT A., TORUN E., et al.

CLINICAL RESPIRATORY JOURNAL, cilt.11, ss.243-247, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 11 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/crj.12331
  • Dergi Adı: CLINICAL RESPIRATORY JOURNAL
  • Sayfa Sayısı: ss.243-247

Özet

IntroductionThe antimicrobial peptides (AMPs) human -defensins and cathelicidin (LL-37) are key factors in innate and adaptive immune responses of the respiratory tract and play an important role in many respiratory diseases. No data are available in the literature about the levels of these AMPs in paediatric patients with post-infectious bronchiolitis obliterans (BO). This study aimed to determine human -defensin 2 (hBD2) and LL-37 levels and compare between post-infectious BO patients and the control group.