Cathelicidin (LL-37) and human 2-defensin levels of children with post-infectious bronchiolitis obliterans


Gedik A. H. , ÇAKIR E., GÖKDEMİR Y., Uyan Z. S. , KOÇYİĞİT A., TORUN E., ...More

CLINICAL RESPIRATORY JOURNAL, vol.11, pp.243-247, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1111/crj.12331
  • Title of Journal : CLINICAL RESPIRATORY JOURNAL
  • Page Numbers: pp.243-247

Abstract

IntroductionThe antimicrobial peptides (AMPs) human -defensins and cathelicidin (LL-37) are key factors in innate and adaptive immune responses of the respiratory tract and play an important role in many respiratory diseases. No data are available in the literature about the levels of these AMPs in paediatric patients with post-infectious bronchiolitis obliterans (BO). This study aimed to determine human -defensin 2 (hBD2) and LL-37 levels and compare between post-infectious BO patients and the control group.