Eğitim Bilgileri
2008 - 2012
2008 - 2012Doktora
The University of Manchester, Faculty Of Life Sciences, Birleşik Krallık
2005 - 2007
2005 - 2007Yüksek Lisans
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyoteknoloji (Yl) (Tezli), Türkiye
2001 - 2005
2001 - 2005Lisans
Ankara Üniversitesi, Fen Fakültesi, Biyoloji Bölümü, Türkiye
Yaptığı Tezler
2012
2012Doktora
Assessment of the influence of chromatin elements on stability of recombinant protein production in amplified CHO cells
The University Of Manchester, Faculty Of Life Sciences
2007
2007Yüksek Lisans
Polymerase chain reaction (PCR) for detection of Borrelia burgdorferi sensu lato
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyoteknoloji (Yl) (Tezli)
Araştırma Alanları
Biyoinformatik
Biyoteknoloji
Moleküler Biyoloji ve Genetik
Akademik Unvanlar / Görevler
2017 - Devam Ediyor
2017 - Devam EdiyorDr.Öğr.Üyesi
Kocaeli Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji
2013 - 2017
2013 - 2017Araştırma Görevlisi
Kocaeli Üniversitesi, Biyoloji Bölümü
Yönetimsel Görevler
2014 - Devam Ediyor
2014 - Devam EdiyorErasmus Programı Kurum Koordinatörü
Kocaeli Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji
Verdiği Dersler
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
2023
2023Long term culture promotes changes to growth, gene expression, and metabolism in CHO cells that are independent of production stability
Torres M., BETTS Z., Scholey R., Elvin M., Place S., Hayes A., et al.
Biotechnology and Bioengineering , cilt.120, sa.9, ss.2389-2402, 2023 (SCI-Expanded)
2023
2023Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells
BETTS Z., Deveci Ozkan A., YÜKSEL B., Alimudin J., AYDIN D., AKSOY Ö., et al.
Journal of Toxicology and Environmental Health - Part A: Current Issues , cilt.86, sa.22, ss.833-845, 2023 (SCI-Expanded)
2022
2022Anticancer Properties of Eisenia Foetida Proteins in Prostate Cancer Cells In Vitro
Ozkan A. D., Eskiler G. G., SARIHAN M., Kazan N., AKSOY Ö., YÜKSEL B., et al.
International Journal of Peptide Research and Therapeutics , cilt.28, sa.4, 2022 (SCI-Expanded)
2022
2022Evaluation of the antioxidative and genotoxic effects of sodium butyrate on breast cancer cells
Yüksel B., Deveci Ozkan A., Aydın D., Betts Z.
Saudi Journal of Biological Sciences , cilt.29, ss.1394-1401, 2022 (SCI-Expanded)
2022
2022Protective effect of Eisenia foetida coelomic fluid against oxidative damage in human endothelial cells
Kilciler Y., Ozkan A. D., BETTS Z.
TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY , cilt.104, sa.2, ss.307-320, 2022 (SCI-Expanded)
2022
2022In vitro chemo-protective effect of Eisenia foetida coelomic fluid against histone deacetylase inhibitor-induced oxidative toxicity in breast cancer cells
Ozkan A. D., Alimudin J., Kilciler Y., YÜKSEL B., AKSOY Ö., BETTS Z.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH , cilt.33, sa.12, ss.1728-1737, 2022 (SCI-Expanded)
2020
2020Metabolic profiling of Chinese hamster ovary cell cultures at different working volumes and agitation speeds using spin tube reactors
Torres M., Elvin M., Betts Z., Place S., Gaffney C., Dickson A.
Biotechnology Progress , ss.3099-3118, 2020 (SCI-Expanded)
2017
2017Improved CHO Cell Line Stability and Recombinant Protein Expression During Long-Term Culture
BETTS Z., Dickson A. J.
HETEROLOGOUS PROTEIN PRODUCTION IN CHO CELLS: METHODS AND PROTOCOLS , cilt.1603, ss.119-141, 2017 (SCI-Expanded)
2016
2016Ubiquitous Chromatin Opening Elements (UCOEs) effect on transgene position and expression stability in CHO cells following methotrexate (MTX) amplification
Betts Z., Dickson A. J.
BIOTECHNOLOGY JOURNAL , cilt.11, sa.4, ss.554-564, 2016 (SCI-Expanded)
2015
2015Assessment of UCOE on Recombinant EPO Production and Expression Stability in Amplified Chinese Hamster Ovary Cells
Betts Z., Dickson A. J.
MOLECULAR BIOTECHNOLOGY , cilt.57, sa.9, ss.846-858, 2015 (SCI-Expanded)
2015
2015Evaluating the interaction between UCOE and DHFR-linked amplification and stability of recombinant protein expression
Betts Z., Croxford A. S., Dickson A. J.
BIOTECHNOLOGY PROGRESS , cilt.31, sa.4, ss.1014-1025, 2015 (SCI-Expanded)
2009
2009Seroprevalence of bovine leptospirosis in Kayseri, Turkey and detection of leptospires by polymerase chain reaction
GÜMÜŞSOY K. S., Ozdemir V., AYDIN F., Asian O., Atabek E., lea T., et al.
Journal of Animal and Veterinary Advances , cilt.8, sa.6, ss.1222-1229, 2009 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
2023
2023DETERMINATION OF THE EFFECT OF RUTIN ON EPITHELIAL TO MESENCHYMAL TRANSITION IN PROSTATE CANCER CELLS
Bal E., ÖZKAN A. D., Betts Z.
Acta Medica Nicomedia , cilt.6, sa.1, ss.131-136, 2023 (Hakemli Dergi)
Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar
2019
2019Stability of recombinant protein production in CHO cell lines: A molecular approach
BETTS Z., Place S., DICKSON A. J.
BioProNET 6th Annual Science Meeting, 3 - 04 Haziran 2019
2019
2019Molecular Mechanism of rekombinant protein production instability
BETTS Z., Ramberg V., Barsoum E., Ingrid L., Smith D., DICKSON A. J., et al.
26th ESACT Meeting, 5 - 08 Mayıs 2019
2018
2018Instability in CHO cells: Diagnosis and Cure
BETTS Z., Place S., DICKSON A. J.
BioProNET 5th Annual Science Meeting, 10 - 11 Ekim 2018
2015
2015Effect of Sodium Butyrate on the Surrounding Chromatin Environment in AMplified CHO cells
BETTS Z., Alan J D.
International Conference on Biochemistry and Molecular Biology, Paris, Fransa, 22 - 23 Nisan 2015
2014
2014Effect of transgene location on productivity and stability of recombinant protein expression
BETTS Z., Alan J D.
European Federation of Biotechnology, Focus on Frontiers in Industrial Biotechnology, Londrina, Brezilya, 17 Kasım 2014 - 19 Kasım 2013
2014
2014Sodyum butiratin amplifiye edilmis CHO hucrelerinde rekombinant protein ekspresyonuna etkisi
BETTS Z., Alan J D.
22. Ulusal Biyoloji kongresi, Eskişehir, Türkiye, 23 - 27 Haziran 2014
2011
2011Stability of recombinant protein production in amplified CHO cells
BETTS Z., DICKSON A. J., Croxford A. S.
22nd European Society for Animal Cell Technology Meeting, Viyana, Avusturya, 15 - 18 Mayıs 2011
2010
2010Stability of recombinant protein production in Chinese Hamster Ovary Cells
BETTS Z., Croxford A. S., DICKSON A. J.
20th Annual Conference ESACT-UK, UK Society for Cell Culture and Biotechnology, Loughborough, Birleşik Krallık, 6 - 07 Ocak 2010
2009
2009Stability of recombinant protein production in amplified Chinese hamster ovary cells
BETTS Z., DICKSON A. J., Croxford A. S.
9th Conference on Protein Expression in Animal Cells, Jackson Hole, Amerika Birleşik Devletleri, 19 - 23 Eylül 2009
Kitap & Kitap Bölümleri
2017
2017Improved CHO Cell Line Stability and Recombinant Protein Expression During Long-Term Culture
BETTS Z., DICKSON A. J.
Heterologous Protein Production in CHO Cells, Paula Meleady, Editör, Springer, New-York, ss.119-141, 2017
Burslar
2019 - 2019
2019 - 2019UKRI BBSRC Flexible Talent Mobility Account
Diğer Uluslararası Organizasyonlar
2018 - 2019
2018 - 20192219-Yurtdışı Doktora sonrası araştırma bursu
TÜBİTAK
2008 - 2012
2008 - 2012Yurt Dışı Doktora Bursu
Milli Eğitim Bakanlığı
2005 - 2007
2005 - 2007Yurt İçi Yüksek Lisans Bursu
TÜBİTAK
2002 - 2005
2002 - 2005