ENDOCRINE, vol.57, no.1, pp.148-155, 2017 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Acromegaly, Cathepsin B, Matrix metalloproteinase-2, Matrix metalloproteinase-9, HUMAN PITUITARY-ADENOMAS, IGF-I, DIAGNOSTIC-VALUE, GROWTH-HORMONE, CATHEPSIN-B, GH, METAANALYSIS, DISCREPANT, EXPRESSION, PROTEASES
Kocaeli University Affiliated:
During follow-up of acromegaly patients, there is a discordance rate of 30% between the measurements of growth hormone and insulin-like growth factor-1 levels. Further tests are required to determine disease activity in patients with discordant results. This study was planned to investigate an association of serum levels of matrix metalloproteinase-2, matrix metalloproteinase-9, and cathepsin B with disease activity in acromegaly patients.