Gene-Expression Profiles in Generalized Aggressive Periodontitis: A Gene Network-Based Microarray Analysis

Guzeldemir-Akcakanat E., Sunnetci-Akkoyunlu D., Orucguney B., ÇİNE N., Kan B., Yilmaz E. B., ...More

JOURNAL OF PERIODONTOLOGY, vol.87, no.1, pp.58-65, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 87 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1902/jop.2015.150175
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.58-65
  • Keywords: Aggressive periodontitis, genes, gingiva, inflammation, microarray analysis, TRANSCRIPTOMES, ANTIBODY
  • Kocaeli University Affiliated: Yes

Abstract

Background: In this study, molecular biomarkers that play a role in the development of generalized aggressive periodontitis (GAgP) are investigated using gingival tissue samples through omics-based whole-genome transcriptomics while using healthy individuals as background controls.