Effect of nitric oxide synthase inhibitors in acute lung injury due to blunt lung trauma in rats

Akgul, Ash; ŞAHİN, DENİZ; Temel, Ugur; ELİÇORA, AYKUT; Dillioglugil, MELTEM; Kir, HALE; ÖZSOY, ÖZGÜR; Yildiz, Kursat; Ozer, Cuneyt; TOPÇU, SALİH

doi:10.5606/tgkdc.dergisi.2019.15936

Effect of nitric oxide synthase inhibitors in acute lung injury due to blunt lung trauma in rats

Akgul A. G., ŞAHİN D., Temel U., ELİÇORA A., Dillioglugil M. Ö., Kir H., ...Daha Fazla

TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, cilt.27, sa.1, ss.63-72, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.5606/tgkdc.dergisi.2019.15936
Dergi Adı: TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.63-72
Anahtar Kelimeler: Acute lung injury, oxidative stress, trauma, PULMONARY CONTUSION, N-ACETYLCYSTEINE, CHEST TRAUMA, L-NAME, ACID, ANTIOXIDANT, MACROPHAGE, MODEL, RESUSCITATION, PATHOGENESIS
Kocaeli Üniversitesi Adresli: Evet

Özet

Background: This study aims to investigate the effects of blunt lung trauma performed in experimental rat model on lung tissue and blood as well as proinflammatory cytokines, oxidant-antioxidant enzymes and histopathological parameters after Ngamma-nitro-L-arginine methyl ester and N-iminoethyl-L-ornithine administration.