Comparison of hyperbaric oxygen versus iloprost treatment in an experimental rat central retinal artery occlusion model
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, cilt.254, sa.11, ss.2209-2215, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 254 Sayı: 11
- Basım Tarihi: 2016
- Doi Numarası: 10.1007/s00417-016-3444-5
- Dergi Adı: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.2209-2215
- Anahtar Kelimeler: Retinal artery occlusion, Hyperbaric oxygen therapy, Iloprost, Ischemia-reperfusion injury, ISCHEMIA-REPERFUSION INJURY, CRITICAL LIMB ISCHEMIA, SPINAL-CORD ISCHEMIA, IN-VIVO EVALUATION, RABBIT MODEL, HYPERTENSION, DISEASE, ANALOG
- Kocaeli Üniversitesi Adresli: Evet
Özet
Central retinal artery occlusion (CRAO) is one of the serious ophthalmological emergencies with poor visual prognosis. Iloprost is a stable prostacyclin analogue and has prominent anti-edema, anti-inflammatory, vasodilatory, and antiagregant effects. The main objective of this work was to investigate iloprost as an alternative agent versus hyperbaric oxygen (HBO) in the treatment of CRAO.