Zaprinast and rolipram enhances spatial and emotional memory in the elevated plus maze and passive avoidance tests and diminishes exploratory activity in naive mice.

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Akar F., MUTLU O., Komsuoglu Celikyurt I., ULAK G., Erden F., BEKTAŞ E., ...Daha Fazla

Medical science monitor basic research, cilt.20, ss.105-11, 2014 (Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2014
  • Doi Numarası: 10.12659/msmbr.891149
  • Dergi Adı: Medical science monitor basic research
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.105-11
  • Anahtar Kelimeler: Behavior, Animal, Memory, Mice
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Background: Phosphodiesterase (PDE) inhibitors in the central nervous system have been shown to stimulate neuronal functions and increase neurogenesis in Alzheimer disease (AD) patients.