Use of Adipose-Derived Mesenchymal Stem Cells to Increase Viability of Composite Grafts

Yucel E., Alagöz M. Ş., Eren G. G., Yaşar E. K., Izmırlı H. H., Duruksu G., ...Daha Fazla

JOURNAL OF CRANIOFACIAL SURGERY, cilt.27, ss.1354-1360, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1097/scs.0000000000002707
  • Dergi Adı: JOURNAL OF CRANIOFACIAL SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1354-1360
  • Anahtar Kelimeler: Composite grafts, neovascularization, stem cell, HYPERBARIC-OXYGEN THERAPY, SKIN FLAP, SURVIVAL, TISSUE, RATS, DIFFERENTIATION
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objective: Chondrocutaneous composite grafts figure among the reconstruction alternatives for alar rim defects resulting from tumor resection and trauma. The major problem with composite grafts is the limited graft survival area. In the present study, the authors aimed to increase the survival area of composite grafts by utilizing the ability of stem cells to promote neovascularization which is crucial in composite graft viability.