Akademik Veri Yönetim Sistemi
Türk Nöroşirürji Derneği 37. Bilimsel Kongresi, Antalya, Türkiye, 18 - 21 Nisan 2024, cilt.1, sa.1, ss.168-169
Objective: Central nervous system (CNS) tumors are the most common solid tumors in pediatric population, leading to cancer-related deaths. Current study aims to evaluate the impact of infratentorial or supratentorial location in pediatric cases under 5 years of age with surgically treated intracranial CNS-tumors, based on the parameters such as histopathological diagnosis, postoperative complications and survival-rates.
Methods: Clinical data of 84 patients who have undergone surgicaltreatment for intracranial CNS-tumors at two centers between 2008 and 2024 were retrospectively analyzed. Age, gender, histopathological diagnosis, WHO classification, postoperative complications, and survival-rates were compared according to infratentorial and supratentorial locations.
Results: 39 cases (13 females, 26 males) were supratentorial, and 45 cases (25 females, 20 males) were infratentorial (p>0,05). The mean age was 37.04±18.78 months for the infratentorial-group and 30.74±20.09 months for the supratentorial-group (p>0,05). The most common postoperative complication was hydrocephalus in both groups (23% in the supratentorial-group, 33% in the infratentorial-group) (p>0.05). The fiveyear survival rate was calculated as 72±8.2% in the supratentorial-group and 67.6±7.5% in the infratentorial-group. There was no statistically significant difference in cumulative survival rates between two groups.
Conclusion: Despite the recent proceedings in diagnosis and treatment protocols, intracranial CNS-tumors are still challenging in pediatric neurosurgery practice. The data of the current study suggest that there seems to be no statistically significant difference between infratentorial and supratentorial locations of intracranial CNS-tumors among children under five years of age regarding the parameters of postoperative complication rate and cumulative survival-rate. These findings should be validated by further detailed multicenter studies.
Keywords: Pediatric, tumor, location