Pulmonary to Systemic Flow Ratio in Precapillary Pulmonary Hypertension Without Left-to-Right Shunts: A Prognostic Implication of the Fick Method

ŞENTÜRK B., AKDENİZ B., YILMAZ M. B. , ÖZPELİT E., SEZGİN D., Kahraman B. O. , ...More

MEDICAL JOURNAL OF BAKIRKOY, vol.17, no.3, pp.227-232, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.4274/bmj.galenos.2021.67044
  • Page Numbers: pp.227-232
  • Keywords: Pulmonary hypertension, prognosis, fick method, oxygen, mortality, VENOUS OXYGEN-SATURATION, LONG-TERM SURVIVAL, ARTERIAL-HYPERTENSION, BLOOD


Objective: We routinely calculate the pulmonary to systemic (Qp/Qs) ratio to avoid missing any left-to-right shunts in patients with precapillary pulmonary hypertension (PH). However, the pulmonary artery oxygen saturation (SpaO(2)) was lower than the mixed venous oxygen saturation (SmvO(2)) calculated using the formula; hence, the Qp/Qs ratio was calculated as less than "1" in some patients despite the absence of any detectable shunt. We hypothesized that this observation might have prognostic significance; however, to the best of our knowledge, it has not been investigated yet. Therefore, we aimed to examine the prognostic value of the Qp/Qs ratio in precapillary PH without left-to-right shunts.