Biochemical effects of experimental epidural hematoma on brain parenchyma of rats
NEUROLOGICAL RESEARCH, vol.30, no.5, pp.450-456, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 30 Issue: 5
- Publication Date: 2008
- Doi Number: 10.1179/016164107x251637
- Journal Name: NEUROLOGICAL RESEARCH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.450-456
- Kocaeli University Affiliated: Yes
Abstract
Introduction: The management of epidural hematoma is classified into surgical or conservative treatment according to clinical and radiologic parameters. In the recent years, the number of paper suggesting conservative management has been increasing. The experimental works that have been performed are based on especially the effects of epidural hematomas. Basic pathophysiologic factors on ischemia result of brain trauma are based on biochemical mediators. Nitric oxide (NO) and malondialdehyde (MDA) are the substances that play important roles in brain damage after trauma.