Treatment-induced manic switch in the course of unipolar depression can predict bipolarity: Cluster analysis based evidence


Dumlu K., Orhon Z., Ozerdem A., TURAL Ü. , ULAŞ H., TUNCA Z.

JOURNAL OF AFFECTIVE DISORDERS, vol.134, pp.91-101, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 134
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jad.2011.06.019
  • Title of Journal : JOURNAL OF AFFECTIVE DISORDERS
  • Page Numbers: pp.91-101

Abstract

Background: Antidepressants are known to induce manic switch in patients with depression. Treatment-induced mania is not considered as bipolar disorder in DSM IV. The aim of this study was to assess whether clinical characteristics of patients with unipolar depression with a history of treatment-induced mania were similar to those of patients with bipolar disorder.