Treatment-induced manic switch in the course of unipolar depression can predict bipolarity: Cluster analysis based evidence

Dumlu, Kemal; Orhon, Zahide; Ozerdem, Ayegul; TURAL, ÜMİT; ULAŞ, HALİS; TUNCA, ZELİHA

doi:10.1016/j.jad.2011.06.019

Treatment-induced manic switch in the course of unipolar depression can predict bipolarity: Cluster analysis based evidence

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Dumlu K., Orhon Z., Ozerdem A., TURAL Ü., ULAŞ H., TUNCA Z.

JOURNAL OF AFFECTIVE DISORDERS, vol.134, pp.91-101, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 134
Publication Date: 2011
Doi Number: 10.1016/j.jad.2011.06.019
Journal Name: JOURNAL OF AFFECTIVE DISORDERS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
Page Numbers: pp.91-101
Kocaeli University Affiliated: Yes

Abstract

Background: Antidepressants are known to induce manic switch in patients with depression. Treatment-induced mania is not considered as bipolar disorder in DSM IV. The aim of this study was to assess whether clinical characteristics of patients with unipolar depression with a history of treatment-induced mania were similar to those of patients with bipolar disorder.