SARS-Cov2-Induced Cytokine Storm and Schizophrenia, Could There be a Connection? Citokinska oluja izazvana SARS-Cov2 i shizofrenija, postoji li povezanost?
Archives of psychiatry research, cilt.58, sa.1, ss.107-118, 2022 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 58 Sayı: 1
- Basım Tarihi: 2022
- Doi Numarası: 10.20471/may.2022.58.01.12
- Dergi Adı: Archives of psychiatry research
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.107-118
- Anahtar Kelimeler: COVID-19, inflammation, olfactory ce, SARS-CoV-2, schizophrenia
- Kocaeli Üniversitesi Adresli: Evet
Özet
Today, a new coronavirus (2019-nCoV, later named SARS-CoV-2) has become known as a pandemic with over 3,949,200 cases and 271,782 deaths. It has been considered that most of the deaths in infected patients stem from co-morbidity conditions. Therefore, understanding at-risk populations are currently under the focus of investigations. This object has highly driven attention to put patients with a higher potential of death related to SARS-CoV2 infection at priority. For instance, this can happen in Schizophrenia owing to ambiguous immunology attributes, including elevated levels of pro-inflammatory cytokines and stress-related immune disability. Given that, the hyper-inflammatory responses are the significant cause of the pathophysiology of the SARS-CoV2-related mortality. Moreover, SARS-CoV2 can prompt the risk of developing Schizophrenia in the future. This review punctuates that prenatal/perinatal infection could be associated with increased Schizophrenia risk; on the flip side, the potential risk of ongoing medication can worsen mentally disabled patients, and healthy people are at risk.