Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.

Maraş, Genç; Uyur, Yalçın; Sayan, MURAT; Bayhan, A; Öncel, SELİM; Arısoy, EMİN; Kara, BÜLENT

doi:10.1016/j.jcv.2016.05.002

Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.

Maraş G., Uyur Y., Sayan M., Bayhan A., Öncel S., Arısoy E. S., ...Daha Fazla

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, cilt.80, ss.87-92, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 80
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.jcv.2016.05.002
Dergi Adı: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.87-92
Anahtar Kelimeler: Herpes simplex virus, Encephalitis, Children, Steroids, Outcome, VIRUS-ENCEPHALITIS, COMBINATION THERAPY, ADULT PATIENTS, ACYCLOVIR, INFECTIONS
Kocaeli Üniversitesi Adresli: Evet

Özet

Background: Herpes simplex virus encephalitis (HSE) is a significant cause of morbidity and mortality. Neurologic sequelae are common even after early initiation of acyclovir treatment. The host immune response during HSE can also lead to brain damage. There are an increasing number of reports favoring steroid use in HSE.