Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.

Maraş, Genç; Uyur, Yalçın; Sayan, MURAT; Bayhan, A; Öncel, SELİM; Arısoy, EMİN; Kara, BÜLENT

doi:10.1016/j.jcv.2016.05.002

Clinical outcomes in children with herpes simplex encephalitis receiving steroid therapy.

Maraş G., Uyur Y., Sayan M., Bayhan A., Öncel S., Arısoy E. S., ...More

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, vol.80, pp.87-92, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 80
Publication Date: 2016
Doi Number: 10.1016/j.jcv.2016.05.002
Journal Name: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.87-92
Keywords: Herpes simplex virus, Encephalitis, Children, Steroids, Outcome, VIRUS-ENCEPHALITIS, COMBINATION THERAPY, ADULT PATIENTS, ACYCLOVIR, INFECTIONS
Kocaeli University Affiliated: Yes

Abstract

Background: Herpes simplex virus encephalitis (HSE) is a significant cause of morbidity and mortality. Neurologic sequelae are common even after early initiation of acyclovir treatment. The host immune response during HSE can also lead to brain damage. There are an increasing number of reports favoring steroid use in HSE.