Effects of opioid-type stressors on serum digoxin-like immunoreactivity in rats


Uresin Y., Eroglu L., Yildiran G.

METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, vol.18, pp.569-571, 1996 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 9
  • Publication Date: 1996
  • Title of Journal : METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
  • Page Numbers: pp.569-571

Abstract

The effects of opioid-type stressors (immobilization, electric footshock and forced swimming) on serum digoxin-like immunoreactivity (SDLI) were investigated in rats. All of the stressors significantly elevated the SDLI. Naloxone treatment after application of stressors prevented the elevation of SDLI, whereas naloxone treatment alone did not cause any significant changes. The observed increase in SDLI in this study may be attributed to the actions of endogenous opioid peptides released during stress.