Excessive gingival bleeding in two patients with glanzmann thrombasthenia

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Toygar H. U., Guzeldemir E.

JOURNAL OF PERIODONTOLOGY, vol.78, no.6, pp.1154-1158, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 78 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1902/jop.2007.060393
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1154-1158
  • Keywords: gingival bleeding, glanzmann thrombasthenia, oral hygiene
  • Kocaeli University Affiliated: No

Abstract

Background: Glanzmann thrombasthenia (GT) is an exceedingly rare but well-defined inherited disorder of platelet function caused by a defect in the glycoprotein IIb/IIIa complex. The association of GT with consanguinity has been noted, especially in geographic regions in which intermarriage is common. In most patients, GT is diagnosed during early infancy or before the age of 5 years. Common manifestations of this disorder are gingival hemorrhage, purpura, epistaxis, petechiae, and menorrhagia. Chronic, prolonged, untreated, or unsuccessfully treated bleeding may be life threatening.