Excessive gingival bleeding in two patients with glanzmann thrombasthenia


Toygar H. U. , Guzeldemir E.

JOURNAL OF PERIODONTOLOGY, cilt.78, ss.1154-1158, 2007 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 78 Konu: 6
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1902/jop.2007.060393
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Sayfa Sayısı: ss.1154-1158

Özet

Background: Glanzmann thrombasthenia (GT) is an exceedingly rare but well-defined inherited disorder of platelet function caused by a defect in the glycoprotein IIb/IIIa complex. The association of GT with consanguinity has been noted, especially in geographic regions in which intermarriage is common. In most patients, GT is diagnosed during early infancy or before the age of 5 years. Common manifestations of this disorder are gingival hemorrhage, purpura, epistaxis, petechiae, and menorrhagia. Chronic, prolonged, untreated, or unsuccessfully treated bleeding may be life threatening.