Manganese(III) acetate mediated synthesis of 3-triluoroacetyl-4,5-dihydrofurans and 3-(dihydrofuran-2(3H)-ylidene)-1,1,1-triluoroacetones by free radical cyclization. Part 1


Yilmaz M. , PEKEL A. T.

JOURNAL OF FLUORINE CHEMISTRY, vol.126, pp.401-406, 2005 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 126 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.1016/j.jfluchem.2005.02.002
  • Title of Journal : JOURNAL OF FLUORINE CHEMISTRY
  • Page Numbers: pp.401-406

Abstract

2-Trifluoroacetyl-4,5-dihydrofurans were obtained by manganese(III) acetate mediated radical cyclization of trifluoromethyl-1,3dicarbonyl compounds (1a-c) with conjugated alkenes (2a-h). The reaction of 1,1,1-trifluoropentane-2,4-dione (1a) with propenylbenzene and 1,1-diphenyl-l-butene surprisingly yielded 3-(dihydrofuran-2(3H)-ylidene)-1,1,1-trifluoroacetones besides 3-trifluoroacetyl-4,5-dihydrofurans. (c) 2005 Published by Elsevier B.V.