Decreased serum levels of glycerol-3-phosphate dehydrogenase 1 and monoacylglycerol lipase act as diagnostic biomarkers for breast cancer

Yoneten K. K., Kasap M., Arga K. Y., Akpinar G., Utkan N. Z.

CANCER BIOMARKERS, vol.34, no.1, pp.67-76, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.3233/cbm-203093
  • Journal Name: CANCER BIOMARKERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.67-76
  • Keywords: Breast cancer, monoacylglycerol lipase, glycerol-3-phosphate dehydrogenase, diagnostic biomarkers, ELISA, LIPID-METABOLISM, HIGHLIGHTS, PROGNOSIS, SYNTHASE, CELLS
  • Kocaeli University Affiliated: Yes

Abstract

BACKGROUND: Breast cancer (BC) is one of the most life-threatening cancer types among women. Despite major developments in medical sciences and technologies, the incidence and mortality rates of BC cases are still increasing. One of the reasons for this increase is the absence of an easy to perform early-diagnostic tool. Although there are defined BC biomarkers routinely used for diagnostic and prognostic purposes, none of these biomarkers is useful for early diagnosis. Therefore, early diagnosis of BC remains an important challenge and there is a great need for the early-diagnostic biomarker(s).