Which Patients with Dilated Cardiomyopathy Have Left Atrial Spontaneous Echo Contrast?

Kozdag G., VURAL A., Ozden M., ŞAHİN T., Ural D., AĞAÇDİKEN AĞIR A., ...Daha Fazla

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.33, sa.1, ss.2-9, 2005 (ESCI, Scopus, TRDizin)

Özet

Objectives: Left atrial spontaneous echo contrast (LA-SEC) detected by transesophageal echocardiography (TFE) is a strong predictor for thromboembolic events. Few studies investigated the related conditions that lead to appearance of LA-SEC in dilated cardiamyopathy (DCMP) patients. The aim of the study was to investigate the prevalence of LA-SEC in patients with DCMP and to determine its related parameters. Methods: Consecutive patients (29 female, 65 male, mean age 60 11 years) with the diagnosis of ischenuc (n=56) and non-ischemic (n=38) DCMP underwent laboratory, transthoracic and TEE examination. Results: LA-SEC was established in 48 patients (51%) of study group. LA-SEC was detected in 33 (59%) of ischemic DCMP and 15 (39%) of 11011-ischemic patients. In ischemic DCMP, restrictive diastolic filling (RDF) was observed 36% of the patients with LA-SEC vs. 22% in the patients without LA-SEC(1)=0.05). Atrial fibrillation (AF) was present in 42% vs. 17% (p=0.05), hypertension was present 67% vs 39% of the patients respectively. In patients with ischemic DCMP, another significant correlate of LA-SEC was high fibrinogen level (471 +/- 78 Ingldi vs. 392 +/- 83 ntgldl, p=0.003). In nomischemic DCMP group, AF was observed in 53% of the patients with LA-SEC is. in 13% of the patients without LA-SEC (p=0.01). In patients with non-ischemic DCMP other significant determinants for LA-SEC were increased age (65 +/- 6 years vs. 53 +/- 12 years, p<0.001), decreased cardiac index (2.1 +/- 0.6 Llininlm(2) vs. 2.7 +/- 0.6 LIntinlm(2), p=0.009) and reduced left atrial appendagel)clocities (p<0.00I). Conclusions: In patients with DCMP, LA-SEC is frequently detected in patients with AF. In RCMP frequency of RDF and hypertension, and high fibrinogen level, in non-ischemic DCMP increased age and low cardiac index appeared as other correlates of LA-SEC.