The world has faced Covid-19, a serious threat to human health since the beginning of 2020. Determination of factors affecting Covid-19-related deaths is very important for the fight against virus and has been the subject of many studies. Multi criteria decision making methods support the decision maker to reach an effective result by providing the opportunity to evaluate all factors that may affect the decision problem. In this study, we examined the factors that constitute the risk group of Covid-19 disease in accordance with the multi criteria decision making structure. With DEMATEL (Decision Making Trial and Evaluation Laboratory) method we evaluated the generally accepted factors for the disease from a different perspective. We have compiled data from the literature and identified the factors referenced in various sources. We analyzed the levels of influence of these risk factors, known to be effective on deaths, by making numerical analyzes for different threshold values that we determined according to the spread of the virus. We obtained results that can be taken as a basis in terms of the strategies to be applied for virus spread process. Finally, we interpreted the multi-criteria analysis results in accordance with the basic principles of the DEMATEL method.