Effect of pentoxifylline on healing of segmental bone defects and angiogenesis

Cakmak G., Sahin M. S., Ozdemir B. H., Karadeniz E.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.49, sa.6, ss.676-682, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3944/aott.2015.15.0158
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.676-682
  • Anahtar Kelimeler: Bone graft, bone healing, cortical defect, pentoxifylline, ISCHEMIA-REPERFUSION INJURY, SPINAL-CORD ISCHEMIA, PROTEIN-KINASE-A, ENDOTHELIAL-CELLS, PARATHYROID-HORMONE, NEUTROPHIL MIGRATION, OVARIECTOMIZED RATS, SKELETAL-MUSCLE, RABBITS, MICE
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Objective: The aim of this study was to determine the effect of pentoxifylline (PTX) on angiogenesis and the healing of a critical-sized segmental defect of the radius diaphysis in a rat model, using radiological and histological grading systems.