A new chiral phosphine oxide ligand for enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides

Eroksuz S., Doğan Ö., Garner P. P.

TETRAHEDRON-ASYMMETRY, cilt.21, sa.20, ss.2535-2541, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 20
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.tetasy.2010.10.002
  • Dergi Adı: TETRAHEDRON-ASYMMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2535-2541
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

A new set of phosphorus-containing chiral ligands has been synthesized and used with silver(I) for the catalytic asymmetric 1 3-dipolar cycloaddition reaction of azomethine ylides One of these ligands (POFAM6) was found to produce an effective catalyst for the asymmetric 1 3 dipolar cycloaddition reaction of azomethine ylides with electron deficient dipolarophiles to form pyrrolidines in up to 97% yield and 89% (C) 2010 Elsevier Ltd All rights reserved