Akademik Veri Yönetim Sistemi
STEM CELLS FOR CANCER AND GENETIC DISEASE TREATMENT, ss.29-59, 2018 (SCI-Expanded)
The first use of umbilical cord stem cells was performed in a child with Fanconi's anemia (a type of congenital anemia), and so far, hundreds of successful stem cell transplantations have been carried out to date; thus, large storage centers have been established in different countries of the world. Researchers suggest that around 30,000 patients are diagnosed with diseases that can be treated with bone marrow stem cells, and about 75% of these patients are not able to find a suitable candidate for bone marrow donation. On the other hand, the search for bone marrow donor registry centers takes a lot of time, thus saving the cord blood to shorten the time and increasing the amount of the donor; thus, giving more time to people with genetic disorders and hematologic malignancies such as acute leukemia, anemia, and immunodeficiency that suffer from short life. Today, extensive research is devoted to the treatment of genetic and malignant diseases and lesions, repair of damaged organs and tissue, crucial organs regeneration, and repair of other damaged tissues using various type of stem cells. There are many ways to use stem cells in basic and clinical research. However, technically, there are a lot of limitations in such promising theories in treating diseases and achieving an appropriate treatment method for them, which is only possible through more research and testing. The emergence of new diseases that either did not respond to conventional treatments or did not provide therapeutic treatment at all has led researchers to use therapeutic therapies to treat more effective cell-mediated therapies for severe morbid illnesses.