Negative Viral Load Follow-Up in an Untreated HIV-2-Infected Patient: A Case Report

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Gür-Altunay D., TOYGAR DENİZ M., SAYAN M., AKHAN S.

Infectious Diseases and Clinical Microbiology, vol.8, no.1, pp.94-97, 2026 (ESCI, Scopus, TRDizin) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 1
  • Publication Date: 2026
  • Doi Number: 10.36519/idcm.2026.811
  • Journal Name: Infectious Diseases and Clinical Microbiology
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.94-97
  • Keywords: env protein gp36, HIV, HIV-2, viral load
  • Kocaeli University Affiliated: Yes

Abstract

HIV-2 is endemic in certain regions, particularly West Africa. A 64-year-old Ghanaian male, who had previously lived in Canada and had been residing in Türkiye for the past 10 years, was diagnosed with HIV-2 while living in Canada but had not received antiretroviral therapy. HIV-2 infection was confirmed by fourth-generation ELISA and Geenius™ assay, which demonstrated gp36 and gp140 positivity. The ‘in-house’ HIV-2 proviral DNA test was also positive. Over a three-month follow-up period, HIV-2 RNA remained negative, and CD4+ T lymphocyte levels showed no decline. To the best of our knowledge, this patient is the third reported HIV-2 case in Türkiye.