The most common problem in implants and prosthesis used in the field of orthopedics and dentistry is the loosening. Implants and prosthesis are unable to function due to this problem. Postoperative follow-up and early detection of this loosening problem is very important. Since the methods used in the orthopedics are already having a low success in identifying relaxation, an alternative method has to be developed. In this study, the determination of postoperative loosening using vibration method was evaluated via finite element method. Modeling of femoral bone and hip prosthesis were evaluated by harmonic response analysis. The effect of the changing properties of the material in the femoral bone was also included in the analysis. As a result of this study, the frequency and amplitude values decreased as the degree of loosening decreased. Thus, it was observed that the vibration method could be successful despite the change in bone density in the postoperative follow-up.