Cyclotriphosphazene, a scaffold for <SUP>19</SUP>F MRI contrast agents
TETRAHEDRON LETTERS, vol.59, no.6, pp.521-523, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 59 Issue: 6
- Publication Date: 2018
- Doi Number: 10.1016/j.tetlet.2017.12.032
- Journal Name: TETRAHEDRON LETTERS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
- Page Numbers: pp.521-523
- Kocaeli University Affiliated: No
Abstract
A cyclotriphosphazene substituted with six 3,5-bis(trifluoromethyl) benzyloxy units was designed as a novel F-19 MRI contrast agent. The resulting molecule has 36 magnetically equivalent fluorine atoms and exhibited suitable MRI properties with high imaging sensitivity, confirming the proof-of-concept as a convenient scaffold for the production of new F-19 MRI contrasts agents. (C) 2017 Elsevier Ltd. All rights reserved.