This study evaluated the pull-out strength of different glass fiber posts and measured volume of cement and voids in the cement in the root canal utilizing micro-computerized tomography (micro-CT) analysis after they were cemented with two different luting cements. Canine teeth (N=40) were endodontically treated and randomly divided into four groups depending on the fiber post and the cement type (n=10 per group) as follows: Group RU: (RelyX+RelyX U200), Group PU: (PINpost+RelyX U200), Group RF: (RelyX+FujiCEM 2), Group PF: (PINpost+FujiCEM 2). Each tooth was scanned using micro-CT and the percentage of cement and void volume at the coronal, middle, and apical levels was calculated. Pull-out tests were performed by applying tensile load parallel to the long axis of the posts (0.5mm/min). Data were analyzed using, ANOVA, Kruskal-Wallis, and Mann-Whitney U tests (alpha=0.05). Regardless of cement type, the percentage (%) of cement volume in the RelyX post groups (RU:31-36; RF:29-40) was significantly higher than that in the PINpost groups (PU:19-23; PF:18-22) (p<0.05). The percentage of void volume at the PINpost groups (PU:6-11; PF:8-13) was significantly lower than that in the RelyX groups (RU:2; RF:3) (p<0.05). No significant differences were observed in pull-out strength (N) between the four experimental groups (RU:358.8 +/- 56.2; RF:299 +/- 64.8; PU:311.9 +/- 61.3; PF:293.1 +/- 91.3) (p>0.05). The micro-CT analysis demonstrated that the percentage of cement and void volumes vary depending on the type of fiber post and cement used. No correlation between cement, void volume, and pull-out strength was observed.