Effects of Nebivolol on Skin Flap Survival: A Randomized Experimental Study in Rats

Gideroglu, Kaan; Alagoz, Sahin; Uygur, Fatih; Evinc, Rahmi; Celikoz, Bahattin; BUĞDAYCI, GÜLER

doi:10.1016/j.curtheres.2008.10.001

Effects of Nebivolol on Skin Flap Survival: A Randomized Experimental Study in Rats

Atıf İçin Kopyala

Gideroglu K., Alagoz S., Uygur F., Evinc R., Celikoz B., BUĞDAYCI G.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.69, sa.5, ss.449-458, 2008 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 69 Sayı: 5
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.curtheres.2008.10.001
Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.449-458
Kocaeli Üniversitesi Adresli: Evet

Özet

BACKGROUND: Skin flaps are among the basic treatment options in the reconstruction of soft tissue defects. To improve skin flap survival, a variety of methods, including pharmacologic agents, have been investigated. The effectiveness of anticoagulants, antioxidants, anti-inflammatory drugs, and vasodilatory drugs in improving flap survival has been studied. Nebivolol isa new-generation selective beta(1)-adrenoreceptor blocking agent that has vasodilatory, antithrombotic, antioxidative, and anti-inflammatory effects.