Near infrared-absorbing self-encapsulated phthalocyanine-cored polycaprolactone star polymeric nanoparticles


Yaseen A. N., EMAMI A., Ben Aziza H., DANDAN DOĞANCI M., İŞCİ Ü., Gurek A. G., ...More

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, vol.28, no.02, pp.107-113, 2024 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 28 Issue: 02
  • Publication Date: 2024
  • Doi Number: 10.1142/s1088424624500020
  • Journal Name: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Chimica
  • Page Numbers: pp.107-113
  • Kocaeli University Affiliated: Yes

Abstract

An octahydroxylated photosensitizing Zn phthalocyanine has been used as an initiator in ring-opening polymerization of epsilon-caprolactone. Three different phthalocyanine-core star polymers have been obtained, with each arm functionalized with either 20, 30, or 40 units. To benefit from the absorption of these polymers in the first near-infrared (NIR) phototherapeutic window, the phthalocyanine cores have been self-encapsulated into their polycaprolactone arms to yield biocompatible star polymeric nanoparticles exhibiting a remarkable absorption centered at 782 nm and an excellent logarithmic extinction coefficient value in water.