A new and convenient synthesis of some substituted thiohydantoins

Durust Y., Nohut F.

SYNTHETIC COMMUNICATIONS, cilt.29, sa.11, ss.1997-2005, 1999 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 11
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1080/00397919908086188
  • Dergi Adı: SYNTHETIC COMMUNICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1997-2005
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

3-Substituted thiohydantoins (2a-g) were synthesized in satisfactory yields by the reaction of N-substituted thioureas (1a-g) with chloroacetylchloride in the presence of triethylamine under reflux in dioxane. S-Alkylated products (7, 8) were! obtained from the reaction of 3-p-tolyl -thiohydantoin (2d) with p-nitrobenzylchloride and 3-phenyl-5-chloromethyl-1,2,4-oxadiazole.