In vivo observation of leukocyte-endothelium interaction in ischemia reperfusion injury with the dorsal window chamber and the effects of pentoxifylline on reperfusion injury

Unal, Cigdem; Sen, Cenk; Iscen, Deniz; Dalcik, Hakki

doi:10.1016/j.jss.2006.05.019

In vivo observation of leukocyte-endothelium interaction in ischemia reperfusion injury with the dorsal window chamber and the effects of pentoxifylline on reperfusion injury

Atıf İçin Kopyala

Unal C., Sen C., Iscen D., Dalcik H.

JOURNAL OF SURGICAL RESEARCH, cilt.138, sa.2, ss.259-266, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 138 Sayı: 2
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.jss.2006.05.019
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.259-266
Kocaeli Üniversitesi Adresli: Hayır

Özet

Objective. Ischemia reperfusion injury can cause failure in microsurgical operations. Interaction between leukocytes and endothelium is recognized as an integral step in ischemia reperfusion injury. Pentoxifylline is a methylxanthine derivative that has pharmacological properties that can be beneficial in ischemia reperfusion injury. The aim of this study was to investigate the in vivo effect of pentoxifylline on leukocyte-endothelium interaction in ischemia reperfusion injury.