Charcoal haemoperfusion in amitriptyline poisoning: Experience in 20 children

Bek K. , Oezkaya O., Mutlu B., Dagdemir A., Sungur M., Acikgoez Y., ...More

NEPHROLOGY, vol.13, pp.193-197, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 3
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1440-1797.2008.00922.x
  • Title of Journal : NEPHROLOGY
  • Page Numbers: pp.193-197


Aim: Tricyclic antidepressant (TCA) toxicity is common among children and adults due to widespread use. Amitriptyline (AT) is one of the most commonly prescribed TCAs. Current guidelines do not recommend charcoal haemoperfusion (HP) for AT overdose due to high protein binding and large volume of distribution. However evidence regarding the efficacy of charcoal HP in addition to supportive measures is accumulating in the published reports.