Charcoal haemoperfusion in amitriptyline poisoning: Experience in 20 children

Bek K., Oezkaya O., Mutlu B., Dagdemir A., Sungur M., Acikgoez Y., ...Daha Fazla

NEPHROLOGY, cilt.13, sa.3, ss.193-197, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1440-1797.2008.00922.x
  • Dergi Adı: NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.193-197
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Aim: Tricyclic antidepressant (TCA) toxicity is common among children and adults due to widespread use. Amitriptyline (AT) is one of the most commonly prescribed TCAs. Current guidelines do not recommend charcoal haemoperfusion (HP) for AT overdose due to high protein binding and large volume of distribution. However evidence regarding the efficacy of charcoal HP in addition to supportive measures is accumulating in the published reports.