Alpha-B-crystallin expression in human laryngeal squamous cell carcinoma tissues

YILMAZ M. Y., Karatas O. F., Yuceturk B., Dag H., YENER H. M., ÖZEN M.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, cilt.37, sa.9, ss.1344-1348, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1002/hed.23746
  • Dergi Adı: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1344-1348
  • Anahtar Kelimeler: laryngeal squamous cell carcinoma, B-crystallin, metastasis, quantitative real-time polymerase chain reaction (qRT-PCR), lymph node, HEAT-SHOCK PROTEINS, POOR-PROGNOSIS, SURGERY, MARKER, ANGIOGENESIS, CHEMOTHERAPY, ONCOPROTEIN, METASTASIS, ACTIVATION, RADIATION
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. The recent studies suggested that B-crystallin might play an important role in tumorigenesis. The purpose of this study was to investigate the B-crystallin expression level in metastatic and nonmetastatic laryngeal SCC tissues and to determine its prognostic significance.