Alpha-B-crystallin expression in human laryngeal squamous cell carcinoma tissues

YILMAZ M. Y., Karatas O. F., Yuceturk B., Dag H., YENER H. M., ÖZEN M.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, vol.37, no.9, pp.1344-1348, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.1002/hed.23746
  • Journal Name: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1344-1348
  • Keywords: laryngeal squamous cell carcinoma, B-crystallin, metastasis, quantitative real-time polymerase chain reaction (qRT-PCR), lymph node, HEAT-SHOCK PROTEINS, POOR-PROGNOSIS, SURGERY, MARKER, ANGIOGENESIS, CHEMOTHERAPY, ONCOPROTEIN, METASTASIS, ACTIVATION, RADIATION
  • Kocaeli University Affiliated: No

Abstract

BackgroundLaryngeal squamous cell carcinoma (SCC), being an aggressive malignancy, is one of the most commonly diagnosed malignant types of head and neck SCC worldwide. The recent studies suggested that B-crystallin might play an important role in tumorigenesis. The purpose of this study was to investigate the B-crystallin expression level in metastatic and nonmetastatic laryngeal SCC tissues and to determine its prognostic significance.