Lisinopril Inhibits Endothelin-1 in the Early Period of Hepatic Reperfusion Injury in a Partial Hepatectomy Model


Yirmibesoglu O. A. , BÜYÜKGEBİZ O. , Ars D., Unay O., Cevik D.

TRANSPLANTATION PROCEEDINGS, cilt.43, ss.2524-2530, 2011 (SCI İndekslerine Giren Dergi)

Özet

Background. Ischemia-reperfusion (I/R) injury is a major problem during liver surgery. We investigated the effects of lisinopril, an angiotensin-converting enzyme inhibitor, in the early postoperative period of reperfusion injury after Pringle's maneuver during an 80% partial hepatectomy (PH) in rats.