Lisinopril Inhibits Endothelin-1 in the Early Period of Hepatic Reperfusion Injury in a Partial Hepatectomy Model


Yirmibesoglu O. A. , BÜYÜKGEBİZ O. , Ars D., Unay O., Cevik D.

TRANSPLANTATION PROCEEDINGS, vol.43, no.7, pp.2524-2530, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 7
  • Publication Date: 2011
  • Doi Number: 10.1016/j.transproceed.2011.06.043
  • Title of Journal : TRANSPLANTATION PROCEEDINGS
  • Page Numbers: pp.2524-2530

Abstract

Background. Ischemia-reperfusion (I/R) injury is a major problem during liver surgery. We investigated the effects of lisinopril, an angiotensin-converting enzyme inhibitor, in the early postoperative period of reperfusion injury after Pringle's maneuver during an 80% partial hepatectomy (PH) in rats.