N-acetylcysteine amid reduces pancreatic damage in a rat model of acute necrotizing pancreatitis

TÜRKYILMAZ, SERDAR; Usta, Arif; ÇEKİÇ, ARİF; Alhan, Etem; KURAL, BİRGÜL; Ercin, Cengiz

doi:10.1016/j.jss.2016.03.004

N-acetylcysteine amid reduces pancreatic damage in a rat model of acute necrotizing pancreatitis

Copy For Citation

TÜRKYILMAZ S., Usta A., ÇEKİÇ A. B., Alhan E., KURAL B., Ercin C.

JOURNAL OF SURGICAL RESEARCH, vol.203, no.2, pp.383-389, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 203 Issue: 2
Publication Date: 2016
Doi Number: 10.1016/j.jss.2016.03.004
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.383-389
Kocaeli University Affiliated: Yes

Abstract

Background: Inflammatory explosion and oxidative stress are important mechanisms of injury in acute necrotizing pancreatitis (ANP). This study investigated the effects of N-acetylcysteine amid (NACA), a novel cell-permeant antioxidant with anti-inflammatory activity, on experimental ANP in rats.