N-acetylcysteine amid reduces pancreatic damage in a rat model of acute necrotizing pancreatitis


TÜRKYILMAZ S., Usta A., ÇEKİÇ A. B. , Alhan E., KURAL B., Ercin C.

JOURNAL OF SURGICAL RESEARCH, cilt.203, ss.383-389, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 203 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jss.2016.03.004
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.383-389

Özet

Background: Inflammatory explosion and oxidative stress are important mechanisms of injury in acute necrotizing pancreatitis (ANP). This study investigated the effects of N-acetylcysteine amid (NACA), a novel cell-permeant antioxidant with anti-inflammatory activity, on experimental ANP in rats.