Exenatide Alters Gene Expression of Neural Cell Adhesion Molecule (NCAM), In-tercellular Cell Adhesion Molecule (ICAM), and Vascular Cell Adhesion Molecule (VCAM) in the Hippocampus of Type 2 Diabetic Model Mice

Gumuslu E., ÇİNE N. , Gokbayrak M. E. , MUTLU O. , Celikyurt I. K. , ULAK G.

MEDICAL SCIENCE MONITOR, cilt.22, ss.2664-2669, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 22
  • Basım Tarihi: 2016
  • Doi Numarası: 10.12659/msm.897401
  • Sayfa Sayıları: ss.2664-2669


Background: Glucagon-like peptide-1 (GLP-1), a potent and selective agonist for the GLP-1 receptor, ameliorates the symptoms of diabetes through stimulation of insulin secretion. Exenatide is a potent and selective agonist for the GLP-1 receptor. Cell adhesion molecules are members of the immunoglobulin superfamily and are involved in synaptic rearrangements in the mature brain.