The comparison of weekly and three-weekly cisplatin chemotherapy concurrent with radiotherapy in patients with previously untreated inoperable non-metastatic squamous cell carcinoma of the head and neck.

UYGUN K., Bilici A., KARAGÖL H., Caloglu M., ÇİÇİN İ., Aksu G., ...More

Cancer chemotherapy and pharmacology, vol.64, no.3, pp.601-5, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.1007/s00280-008-0911-7
  • Journal Name: Cancer chemotherapy and pharmacology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.601-5
  • Keywords: Inoperable head and neck cancer, Squamous cell, Weekly cisplatin, Three weekly, Cisplatin, Concurrent chemoradiotherapy, LOCALLY ADVANCED HEAD, RADIATION-THERAPY, RANDOMIZED-TRIAL, PHASE-II, CANCER, ONCOLOGY, EORTC
  • Kocaeli University Affiliated: Yes

Abstract

Several studies have shown that the concurrent administration of chemotherapy (CHT) and radiotherapy (RT) is superior to RT alone in patients with inoperable non-metastatic squamous cell carcinoma of the head and neck (InSCCHN). We compared the efficacy and safety profile of RT and concurrent cisplatin CHT given in two different schedules to patients with previously untreated InSCCHN.