Steroids related to the diterpenoid tumour inhibitor aphidicolin


Hanson J., Hitchcock P., UYANIK C.

JOURNAL OF CHEMICAL RESEARCH-S, no.11, pp.682-686, 1998 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 11
  • Publication Date: 1998
  • Doi Number: 10.1039/a804002h
  • Title of Journal : JOURNAL OF CHEMICAL RESEARCH-S
  • Page Numbers: pp.682-686

Abstract

The syntheses of 2 alpha,17 beta-dihydroxy-2 beta-hydroxymethyl-A-nor-5 alpha-androstane, 3 beta,17 beta-dihydroxy-3 alpha-hydroxymethyl-5 alpha-androstane and 3 beta,17 alpha-dihydroxy-3 alpha-hydroxymethyl-5 alpha,13 alpha-androstane are described, and the stereochemistry of osmylation of a 3-methylene-5 alpha-androstane is established by X-ray crystallography.