Matrix metalloproteinase 2 (MMP-2) levels are increased in active acromegaly patients

Karci A. C. , CANTÜRK Z. , Tarkun I. , Cetinarslan B.

ENDOCRINE, cilt.57, ss.148-155, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 57 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s12020-017-1283-8
  • Dergi Adı: ENDOCRINE
  • Sayfa Sayısı: ss.148-155


During follow-up of acromegaly patients, there is a discordance rate of 30% between the measurements of growth hormone and insulin-like growth factor-1 levels. Further tests are required to determine disease activity in patients with discordant results. This study was planned to investigate an association of serum levels of matrix metalloproteinase-2, matrix metalloproteinase-9, and cathepsin B with disease activity in acromegaly patients.