COVID-19 Vaccines and COVID-19 in People Living with HIV
INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY, cilt.6, sa.2, ss.78-82, 2024 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 2
- Basım Tarihi: 2024
- Doi Numarası: 10.36519/idcm.2024.271
- Dergi Adı: INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.78-82
- Kocaeli Üniversitesi Adresli: Evet
Özet
Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly around the world, and COVID-19 and HIV co-infection also became common. In this study, we aimed to investigate the impact of vaccination preferences and vaccination rates on the severity of COVID-19 in patients with HIV co-infection. Materials and Methods: People living with HIV who were followed in our hospital during the COVID-19 pandemic (January 2020- December 2022) were retrospectively included in the study. The diagnosis of COVID-19 was made by detecting SARS-CoV-2 RNA in nasopharyngeal swab specimens using real -time reverse transcriptase-polymerase chain reaction (rRT-PCR). Patients requiring hospital admission were classified as severe. The patient's demographics and vaccination status were collected from the hospital data system. Results: Our study included 205 patients using antiretroviral therapy for HIV. The mean day count between the last vaccine date and SARS-CoV-2 PCR positivity was 163 days in the Comirnaty (R) group,149 days in the CoronaVac (R) group, and 154 days in the mixed-vaccinated group. Those vaccinated with Comirnaty (R) were statistically significantly less infected with COVID-19 after vaccination ( p <0.05) Conclusion: The course and the outcomes of COVID-19 among SARS-CoV-2 vaccinated people living with HIV, especially with well-controlled HIV infection, seem to be similar to people living without HIV.