Equilibria Studies on Nickel(II) Complexes with 1,10-Phenanthroline Derivatives and Some Amino Acids in Aqueous Solution

İNCİ D., AYDIN R.

JOURNAL OF SOLUTION CHEMISTRY, cilt.50, sa.1, ss.128-146, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s10953-020-01046-3
  • Dergi Adı: JOURNAL OF SOLUTION CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chemical Abstracts Core, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.128-146
  • Anahtar Kelimeler: Ni(ii) complexes, Methyl substituted phenanthrolines, Amino acids, Potentiometry, Stability constants, TRANSITION-METAL IONS, TERNARY COMPLEXES, PALLADIUM(II) COMPLEXES, DISSOCIATION-CONSTANTS, STABILITY-CONSTANTS, COPPER(II) COMPLEX, BINARY, HISTIDINE, LIGAND, PLATINUM(II)
  • Kocaeli Üniversitesi Adresli: Evet

Özet

In recent years, an increase in the biological applications of metal complexes of biologically active ligands has been observed due to their key role in clinical treatments. A potentiometric titration technique has been used to determine the protonation constants of biologically active ligands {glycine (gly), leucine (leu), methionine (met), phenylalanine (phe), tryptophan (trp), asparagine (asn), glutamine (gln), 1,10-phenanthroline (phen), 4-methyl-phenanthroline (4-mphen), 5-methyl-phenanthroline (5-mphen), 3,4,7,8-tetramethyl-1,10-phenanthroline (3,4,7,8-tmphen), 5-nitro-phenanthroline (5-nphen)} and the stability constants of their (1:1) and (1:1:1) complexes with Ni(II) ion (I = 0.100 mol center dot L-1 KCl and T = 298.15 K). The protonation constants of the biologically active ligands and the stability constants of the (1:1) and (1:1:1) complexes of Ni(II) with the biologically active ligands have been computed by using the BEST program. Moreover, the SPE program has been used to determine the distribution of the species that occurred in the aqueous solution medium. The relative stabilities of the (1:1:1) Ni(II) complexes are compared with those of the corresponding (1:1) Ni(II) complexes in terms of Delta log(10)K values. The effect of phenanthroline substituents (4-methyl, 5-methyl, 3,4,7,8-tetramethyl, 5-nitro) on the nature of the Ni(II) complexes is evaluated.