Global Gene Expression Analysis of Reactive Stroma in Prostate Cancer

Dakhova O., Ozen M., Creighton C. J., Li R., Ayala G., Rowley D., ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.15, sa.12, ss.3979-3989, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 12
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1158/1078-0432.ccr-08-1899
  • Dergi Adı: CLINICAL CANCER RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3979-3989
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Purpose: Marked reactive stroma formation, designated as grade 3 reactive stroma, is associated with poor outcome in clinically localized prostate cancer. To understand the biological processes and signaling mechanisms underlying the formation of such reactive stroma, we carried out microarray gene expression analysis of laser-captured reactive stroma and matched normal stroma.