Hypertension and hemostatic/fibrinolytic balance disorders

Tabak O., Gelisgen R., Uzun H., Kalender B., Balci H., Curgunlu A., ...More

CLINICAL AND INVESTIGATIVE MEDICINE, vol.32, no.6, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 6
  • Publication Date: 2009
  • Journal Name: CLINICAL AND INVESTIGATIVE MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Kocaeli University Affiliated: Yes

Abstract

Background: Hypertension is one of the principal risk factors for cardiovascular disease. We aimed to evaluate the impact of hypertension on fibrinolytic balance and endothelial function by measuring plasma levels of plasminogen activator inhibitor-1 (PAI-1), tissue plasminogen activator antigen (tPA), tPA/PAI-1 complex and fibrinogen.